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Isis Pharma Neotone Eyes – dark circles and eyes wrinkles 15 ml. Isis Pharma Neotone Eyes Lightening Eye Contour Care Dark Circles and Eye Bags is a great high gloss cream against dark circles, under the eyes and wrinkles, which features a roller applicator and provides intense care for maintaining a fresh and youthful look. The innovative formula penetrates deeply and smooths the creases, refreshes the eye and rejuvenates the eye contour.